地屈孕酮治疗先兆流产的疗效分析

Study on the Curative Effect of Dydrogesterone in the Treatment of Threatening Abortion

目的对先兆流产应用地屈孕酮治疗的临床疗效进行分析探讨。方法选取于2013年11月～2016年2月在我院接受治疗的先兆流产患者115例,并随机分为对照组（56例）和实验组（59例）,对分别应用黄体酮和地屈孕酮治疗的临床疗效进行对照研究。结果实验组患者的腹痛缓解时间、腰酸缓解时间以及止血时间均短于对照组,血清孕酮值高于对照组,保胎成功率高于对照组（94.92%vs.76.79%）,不良反应发生率低于对照组（8.47%vs.28.57%）,组间差异有统计学意义（P〈0.05）。结论先兆流产应用地屈孕酮治疗的临床疗效十分满意。

Objective Clinical effect of Dydrogesterone in treatment of threatening abortion is to be studied. Methods Chose 115 patients of threatening abortion who were treated in hospital from November 2013 to February 2016 and separated them into control group（56 patients） and study group（59 patients） at random, and then compared clinical effects of Progesterone and Dydrogesterone between two groups. Results Patients＇ abdomen-pain and backache relieved time and their hemostatic time in study group were much shorter than counterparts in control group, and patients＇ serum progesterone value and fetus-protection rate were higher in study group compared to counterparts in control group（94.92% vs. 76.79%）. Besides, patients＇ side-effect incidence in study group was much lower than that in control group（8.47% vs.28.57%）. There was a differential between two groups and such a differential had statistic value（P〈0.05）. Conclusion Patients are quite satisfied with Dydrogesterone efficiency in treatment of threatening abortion.