六味能消胶囊联合兰索拉唑、莫沙必利治疗反流性食管炎的临床效果研究

Study on Clinical Effect of Liu Wei Neng Xiao Capsule Combined With Lansoprazole,Mosapride in the Treatment of Reflux Esophagitis

目的探讨六味能消胶囊联合兰索拉唑与莫沙必利治疗反流性食管炎的临床疗效。方法 152例研究对象均为2015年1～2016年3月我院体检科确诊的反流性食管炎患者,随机分为两组,研究组和对照组,每组各有76例,对照组给予兰索拉唑与莫沙必利治疗,研究组用六味能消胶囊联合兰索拉唑、莫沙必利治疗,对比临床疗效。结果治疗后两组症状积分均较治疗前出现明显下降,差异有统计学意义（P〈0.05）;治疗后研究组的症状积分与对照组比较更低,差异有统计学意义（P〈0.05）。研究组总有效率与对照组比较更高,差异有统计学意义（P〈0.05）。结论反流性食管炎采用六味能消胶囊联合兰索拉唑、莫沙必利治疗效果更好,优势显著,优于应用兰索拉唑与莫沙必利治疗。

Objective To investigate the clinical efficacy of Liu Wei Neng Xiao Capsule Combined with lansoprazole and mosapride in the treatment of reflux esophagitis. Methods From January 2015 to March 2016,152 cases of patients with esophagitis our hospital reflux were selected as the study subjects and were randomly divided into two groups,the study group and the control group,76 cases in each group. Control group received lansoprazole and mosapride,study group was treated with Liu Wei Neng Xiao capsule combined with lansoprazole and mosapride,to compare the clinical efficacy of two groups. Results After treatment,the symptom score decreased significantly compared with before treatment,the difference was statistically significant（P〈0.05）; The symptom score of study group was lower than that of control group after treatment,the difference was statistically significant（P〈0.05）. The total efficiency of the study group was higher than that of control group,the difference was statistically significant（P〈0.05）. Conclusion Application of Liu Wei Neng Xiao Capsule combined with lansoprazole and mosapride in the treatment of reflux esophagitis has significant effects,which is better than application of lansoprazole and mosapride.