米非司酮在无痛人工流产中的应用效果分析

Application effect of mifepristone in painless induced abortion

目的：探讨米非司酮在无痛人工流产中的应用效果。方法选取本院2014年1月～2016年3月早孕要求无痛人工流产的患者268例，将其分为观察组138例和对照组130例。观察组术前16～18 h服用米非司酮6片，实施无痛人工流产术，对照组直接进行无痛人工流产术。结果术中扩宫效果比较，观察组显效124例（89.86%），对照组显效6例（4.62%）；观察组无效1例（0.72%），对照组无效108例（83.07%）。结论服用米非司酮后实施无痛人工流产，术中宫颈松弛自然扩张显著，手术时间缩短，术中出血少，术后7天左右复查B超宫内残留率低，大部分患者阴道出血停止。术前16～18 h服用米非司酮既增加了手术成功率，又有效减少了患者因手术所致的恐惧及并发症，具有临床应用价值。

Objective Explore the clinical effect of mifepristone in painless abortion. Methods Collected in our hospital between January 2014 and March 2014, a total of 268 cases of pregnancy requires painless abortion nulliparity, divided into observation group and control group two groups. Observation group 138 cases, take 6 pieces of mifepristone for the painless abortion preoperative 16~18 h; Control group 130 examples, arranged the time directly in painless abortion. Results Intraoperative comparison the effect of expansion of the cervical, observation group 124 cases were markedly effective, accounted for 89.86%;Control group 6 cases were markedly improved （4.62%？; Observation group is invalid in 1 case （0.72%？,Control group,108 cases of invalid, accounting for 83.07%. Conclusion The painless abortion after taking mifepristone, intraoperative cervical relaxation natural expansion;significantly shorten the operation time,intraoperative bleeding, less postoperative review about 7 d ultrasound intrauterine residual rate is low,the majority of patients stop bleeding. Taking mifepristone preoperative 16~18 h can increased the success rate of surgery, and effectively reduce the patient＇s fear due to surgery and complications, have clinical application value.