清热解毒软胶囊治疗急性扁桃体炎60例

Totally Sixty Cases with Acute Tonsillitis Treated with Heat-Clearing and Toxin-Removing Soft Capsule

目的：观察清热解毒软胶囊治疗急性扁桃体炎的临床疗效。方法：选取120例急性扁桃体炎患者,随机分为对照组和研究组各60例,两组均给予相同西医抗菌抗炎等对症治疗,研究组再予清热解毒软胶囊治疗。观察两组治疗前后相关炎症指标、临床症状体征评分的变化及安全性。结果：两组经治疗后WBC、CRP、PCT水平均较治疗前明显降低（P〈0.01）;研究组治疗后WBC、CRP、PCT水平均低于对照组（P〈0.05）,两组比较差异均有统计学意义。两组经治疗后主症总积分、次症总积分、主次症总积分均较治疗前明显降低（P〈0.01）;研究组治疗后主症总积分、次症总积分、主次症总积分均低于对照组（P〈0.05）,两组比较差异有统计学意义。对照组有效率为88.3%,研究组有效率为98.3%,两组有效率比较差异有统计学意义（χ2=4.821,P=0.028〈0.05）。两组不良反应均未经处理,自行好转,其中对照组不良反应率为13.3%,研究组不良反应率为10.0%,两组不良反应率比较差异无统计学意义（χ^2=0.323,P=0.570〉0.05）。结论：清热解毒软胶囊治疗急性扁桃体炎疗效确切,安全性高,能有效控制炎性反应,改善患者临床症状。

Objective： To observe the clinical effects of Heat-Clearing and Toxin-Removing Soft Capsule on acute tonsillitis. Methods： Totally 120 patients with acute tonsillitis were randomized into control group and research group,with 60 cases in each group. Both groups were given same symptomatic treatment of western medicine anti-bacterial and anti-inflammatory treatment while research group were given Heat-Clearing and Toxin-Removing Soft Capsule for the treatment. The indicators of relevant inflammation,changes of the scores of clinical symptoms and the security before and after the treatment were observed. Results：The levels of WBC,CRP and PCT were all declined greatly after the treatment in both group（ P 〈 0. 01）. And the levels of WBC,CRP and PCT in research group were lower than these in control group（ P 〈 0. 01）,with statistical significance. The total scores of main symptoms,secondary symptoms,main and secondary symptoms after treatment markedly declined compared with before the treatment in both groups（ P 〈 0. 01）; and these scores in research group were lower than those in control group（ P 〈0. 05）; there was significant difference between the two groups. The effective rate was 88. 3% in control group and 98. 3% in research group; the difference between the two groups had statistical significance（ χ2= 4. 821,P = 0. 028 〈 0. 05）. The adverse reaction in both groups didn’t get any treatment but improved automatically. The adverse reaction rate was 13. 3% in control group and 10. 0% in treatment group; the difference had statistical significance（ χ2= 0. 323,P = 0. 570 〉 0. 05）. Conclusion： In treating acute tonsillitis,Heat-Clearing and Toxin-Removing Soft Capsule has definite therapeutic effects and high security,and it can effectively control the inflammatory reaction and improve the clinical symptoms.