血同型半胱氨酸水平与老年人血压及心血管病的相关性分析

Correlation Analysis of Blood Homocysteine Levels and Blood Pressure and Cardiovascular Disease in the Elderly

目的:分析探讨血同型半胱氨酸水平与老年人血压及心血管病的相关性。方法:选取笔者所在医院2015年1月-2016年2月收治的434例老人作为研究对象,其中将218例符合诊断标准和原发性高血压临床症状的老人作为试验组,216例非心脑血管疾病的老人作为对照组,并且分别对两组老人进行空腹静脉血检,观察并分析其血压、颈动脉中膜厚度及Hcy相关情况。结果:试验结果显示,试验组患者的颈动脉中膜厚度与血同型半胱氨酸(Hcy)水平均比对照组患者高,试验组患者的舒张压与收缩压比对照组患者高,两组比较差异均有统计学意义(P<0.05)。血同型半胱氨酸水平与老年人血压及心血管病发生率关系密切(P<0.05)。结论:血同型半胱氨酸水平与老年人血压及心血管病具有相关性,且血压及心血管病的严重程度与血同型半胱氨酸水平呈正比,研究结果希望对临床诊断提供相关参考。

Objective：To analyze the correlation between serum homocysteine levels and blood pressure and cardiovascular disease in the elderly.Method：From January 2015 to February 2016,434 elderly people in our hospital were selected as research subjects,in which 218 met the diagnostic criteria of essential hypertension and clinical symptoms of the elderly as a test group,216 non-cardiac surgical elderly cerebrovascular disease as a control group,and the patients in two groups were fasted for blood check, their blood pressure,carotid artery thickness and Hcy relevant circumstances were observed and analyzed.Result：The test group of patients with carotid artery thickness and blood homocysteine（Hcy） levels were higher than those in the control group,patients in the test group with higher systolic blood pressure and diastolic blood pressure than the control group,there were significant difference in two groups（P〈0.05）.Blood homocysteine levels and blood pressure and the incidence of cardiovascular disease in the elderly were closely related（P〈0.05）.Conclusion：Blood homocysteine levels and blood pressure and cardiovascular disease in the elderly are relevant,and the severity of blood homocysteine levels,blood pressure and cardiovascular disease are directly proportional,the results of clinical diagnostic team hopes to provide relevant information.