内镜下碘染色诊断食管癌前病变的临床分析

Clinical Analysis of Endoscopic Iodine Staining in the Diagnosis of Precancerous Lesions of Esophagus

目的:探讨内镜下碘染色对食管癌和癌前病变的诊断价值。方法:选择2015年6-12月于本院行胃镜活检并存在可疑病灶的184例患者作为研究对象,并对其进行碘染色和病理学检查,分析胃镜下碘染色结果与病理结果之间的关系。结果:184例患者中食管鳞癌42例、不典型增生69例(其中重度12例、中度30例、轻度27例)、慢性食管炎51例以及鳞状上皮增生22例。碘染色后食管癌主要表现为不染,占90.5%(38/42);癌前病变主要表现为不染和淡染,占97.1%(67/69);食管癌及重度不典型增生主要表现为不染,占87.0%(47/54)。结论:食管癌癌前病变在碘染色下主要表现为不染和淡染;碘染色对食管癌和食管癌前病变的筛检具有十分重要的临床价值。

Objective：To investigate the diagnostic value of iodine staining under endoscopy for esophageal cancer and precancerous lesions.Method：One hundred and eighty-four patients with suspicious esophageal lesions under gastroscopic biopsies in our hospital from June 2015 to December 2015 were selected as the objects.All patients were dyed with iodine solution and were given pathological examination.The relationship between the results of pathology and iodine solution staining were collected and analyzed.Result：Among of the 184 patients,42 cases（22.8%） were found with esophageal squalors carcinoma,12 cases（22.8%） with severe esophageal dysplasia,30 cases（16.3%） with moderate esophageal dysplasia,27 cases（14.7%） with mild esophageal dysplasia,51 cases（27.7%） with chronic esophagi and 22 cases（12.0%） with squalors cell hyperplasia.After iodine solution staining,the esophageal cancer were characterized without staining and the proportion was 90.5%（38/42）.The precancerous lesions were characterized with light staining and the proportion was 97.1%（67/69）.The esophageal cancer and severe esophageal dysplasia were characterized without staining and the proportion was 87.0%（47/54）.Conclusion：The esophageal cancer and esophageal dysplasia were characterized without or with light staining under the endoscopic iodine solution staining,which have an important value in the screening of esophageal cancer and precancerous lesions.