肝脏超声造影、增强CT及增强MRI检查肝脏局灶性病变的安全性及耐受性比较

Comparison of safety and tolerance of CEUS,CECT and CEMRI for detection of focal liver lesions

目的比较超声造影(CEUS)与增强CT(CECT)、增强MRI(CEMRI)检查肝脏局灶性病变(FLLs)的安全性及耐受性。方法收集2015年7月在中山大学附属第三医院同时行肝脏CEUS和CECT或CEMRI的肝病患者42例,其中37例同时接受CEUS和CECT检查,36例同时接受CEUS和CEMRI检查。观察检查结束后30 min内有否造影剂不良反应,并采用视觉模拟评分法(VAS)评估检查过程中的不适。结果CEUS和CEMRI的造影剂不良反应发生率低于CECT(0比11%)。患者做CEUS的VAS评分均低于做CECT或做CEMRI的评分(均为P<0.05)。结论肝脏CEUS安全性高且耐受性好,是检查FLLs的首选方法。

Objective To compare the safety and tolerance of contrast-enhanced ultrasound（ CEUS）,contrastenhanced CT（ CECT） and contrast-enhanced MRI（ CEMRI） in the detection of focal liver lesions（ FLLs）. Methods Clinical data of 42 patients undergoing hepatic CEUS and CECT or CEMRI in the Third Affiliated Hospital of Sun Yat-sen University during July 2015 were collected. Among them,37 received CEUS and CECT,and 36 underwent CEUS and CEMRI simultaneously. The contrast agent-induced adverse reaction was observed within 30 min after imaging detection. The severity of discomforts during examination was assessed by visual analog scales（ VAS）. Results The incidence of adverse reaction caused by CEUS and CEMRI contrast agents was lower than that by the CECT contrast agent（ 0 vs. 11%）. The VAS score of patients undergoing CEUS was significantly lower than those of their counterparts receiving CECT or CEMRI（ both P〈0. 05）. Conclusions CEUS is a preferential option for the detection of FLLs with higher safety and better tolerance.