3Ohtani N, Kida K, Shoji K, et al. Recovery profiles from Exme- detomeidine as a general aneshetic adjuvant in patient in patients un- dergoing lower abdominal surgery [ J]. AnesthAnalg, 2008, 107 (6) :1871 - 1874.
5Kunisawa T, Nagata O, Nagashima M, et al. Dexmedetomidine sup- presses the decrease in blood pressure during anesthetic induction and blunts the cardiovascular response totracheal intubafion [ J ]. J Clin Anesth, 2009, 21(3) :194 - 199.
2Gerlach AT, Dasta JF. Dexmedetomidine: an updated review. Ann Pharmaeother, 2007, 41 (2) : 245-252.
3Lakhlani PP, MacMillan LB, GUO TZ, et al. Substitution of a mu- tant alpha2a-adrenergie receptor via "hit and ruan" gene targeting re-veals the role of this subtype in sedative, analgesic, and anesthetic- sparing responses in vivo. Proc Natl Acad Sci USA, 1997, 94(18) : 9950-9955.
4Roekaerts PM, Prinzen FW, de Lange S. Beneficial effects of dexm- edetomidine on ischaemic myocardium of anaesthetized dogs. Br J Anaesth, 1996,77 (3) : 427-429.
5Mantz J. Phase m study on dexmedetomidine used for postoperative sedation of patients requiring mechanical ventilation for less than 24 hours: the French experience. Middle East J Anesthesiol,2002, 16 (6) : 597-606.
6Lawrence CJ, De Lange S. Effects of a single pre-operative dexeme- detomidine dose on isoflurane requirements and peri-operative hemo- dynamic stability. Anaesthesia, 1997,52-736-744.
7Turan G, Ozguhekin A, Turan C, et al. Advantageous effects of dexmedetomidine on haemodynamic and recovery responses during ex- tubation for intracranial surgery. Eur J Anaesthesiol, 2008, 25(10) : 816-820.
8Furst SR, Weinger MB. Dexmedetomidine, a selective alpha2-ago- nist, does not potentiate the cardiorespiratory depression of alfentanil in the rat. Anesthesiology, 1990,72(5) :882-888.
9lelleville JP, Ward DS, Bloor BC, et al. Effects of intravenous [exmedetomidine in humans. I . Sedation, ventilation, and meta- ,olic rate. Anesthesiology, 1992,77 ( 6 ) : 1125-1133.
10Turgut N, Turkmen A, Ali A, et al. Remifentanil-propofol vs dexm- edetomidine-propofol anesthesia for supratentorial craniotomy. Middle East J Anesthesiol, 2009,20( 1 ) : 63-67.