311nm高能紫外线联合卡泊三醇软膏治疗白癜风疗效观察

Clinical efficacy of high energy ultraviolet 311nm combined with Calcipotriol ointment in vitiligo patients

目的：观察311nm高能紫外线联合外用卡泊三醇软膏治疗白癜风的临床效果。方法：选择笔者科室门诊96例白癜风患者（共167处观察部位）,随机分为观察组及对照组。观察组：87处皮损,采用311nm高能紫外线联合卡泊三醇软膏治疗;对照组：80处皮损,仅外涂卡泊三醇软膏治疗,12周后比较两组患者疗效。结果：观察组总有效率74.71%,对照组50.00%,观察组疗效优于对照组,差异有统计学意义（χ^2=10.90,P〈0.01）。结论：311nm高能紫外线联合卡泊三醇软膏治疗稳定期白癜风的临床疗效明显好于单纯外用药物治疗。

Objective To assess the clinical efifcacy of high energy ultraviolet 311nm combined with Calcipotriol ointment in vitiligo patients.Methods 167 lesions of 96 vitiligo patients were enrolled in the clinical trail, and were randomly divided into two groups （the study group and the control group）. High energy ultraviolet 311nm and Calcipotriol ointment were used to treat the 87 lesions in the study group, when Calcipotriol ointment was used to treat the 80 lesions in the control group. The efifcacy and safety were evaluated 12 weeks later.Results The cure rate of the study group was 74.71%, while the number was 50% in the control group. The cure rate showed signiifcant difference between two groups （χ2=10.90,P〈0.05）. Conclusion High energy ultraviolet 311nm combined with Calcipotriol ointment therapy has better efifcacy for stable vitiligo than single treatment.