甘露醇与布林佐胺定联用治疗机械性眼外伤的临床疗效研究

Clinical Effects of mannitol and brinzolamide SDI combined with mechanical treatment of ocular trauma

目的:观察甘露醇结合布林佐胺对机械性眼外伤患者实施治疗的临床治疗效果。方法:选取2012年3月至20153月在我院接受治疗的机械性眼外伤患者312例作为此次研究对象,将其随机分为观察组与对照组,每组患者156例,156例对照组单纯使用甘露醇实施治疗,观察组则使用甘露醇结合布林佐胺实施治疗,对比分析观察组与对照组血肿消失时间以及不良反应出现率、眼压恢复时间等。结果:观察组患者血肿消失时间以及眼压恢复正常的实际均要优于对照组,差异有统计学意义,P<0.05,不良反应的出现率也要比对照组更低,差异有统计学意义,P<0.05。结论:使用甘露醇结合布林佐胺对机械性眼外伤患者实施治疗的临床治疗效果显著,可以在临床中推广使用。

Objective： To observe the combination of mannitol brinzolamide mechanical ocular trauma for patients with clinical effects of treatment. Method： 312 cases for treatment of mechanical ocular trauma patients in our hospital from March 2012 to 2015 were randomly divided into observation group and control group patients with 156 cases in each group. Control group were treated with mannitol, observation group were treated with mannitol in conjunction with brinzolamide, the observation group and the control group hematoma disappeared time and adverse reaction rate, IOP recovery time were compared.Results： Patients in the observation group and the actual time of disappearance of hematoma normal intraocular pressure were better than the control group, with statistical significant,P＆lt;0.05, rate of occurrence of adverse reactions are lower than the control group, with statistical significant,P＆lt;0.05.Conclusion： The combined use of mannitol with brinzolamide mechanical ocular trauma treatment for patients showed clinically significant effects of treatment, thus it can be promoted in clinical use.