中重度阻塞性睡眠呼吸暂停低通气综合征患者经鼻持续气道正压通气治疗后近期生活质量研究

Study on short-term quality of life of nasal continuous positive airway pressure treatment for patients with morderate or severe obstructive sleep apnea hypopnea syndrome

目的分析经鼻持续气道正压通气(n CPAP)对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者近期睡眠疗效、生活质量的影响。方法选择100例中、重度OSAHS患者作为研究对象,根据治疗情况分为n CPAP组(n=60)和未治疗组(n=40),同时选择同期本院门诊健康体检者20例作为对照组,比较n CPAP组、未治疗组的多导睡眠图(PSG)监测结果、魁北克睡眠问卷(QSQ)评分。结果治疗后4周,n CPAP组呼吸暂停通气指数(AHI)、最低血氧饱和度、3+4期睡眠比例、快速动眼睡眠比例均优于治疗前及未治疗组(P<0.05);治疗后n CPAP组QSQ各维度评分及总分均高于治疗前及未治疗组(P<0.05),低于对照组(P<0.05)。结论n CPAP是治疗中、重度OSAHS的有效手段,可以显著改善患者的近期睡眠和生活质量。

Objective To investigate the effect of nasal continuous positive airway pressure （nCPAP）on the quality of life and sleep quality for patients with moderate or severe obstructive sleep apnea hypopnea syndrome （OS-AHS）.Methods 100 patients with moderate or severe OSAHS in our hospital from Ocotober 2014 to March 2015 were selected and divided into nCPAP group （n =60）and untreated group （n =20）according to the treatment 20 healthy cases were collected as control group.The polysomnography （PSG）test results,Quebec sleep questionnaire （QSQ） score,and PSG were compared between the groups.Results After treatment,the apnea hypopnea index （AHI）,the low-est oxygen saturation,the ratio of 3 ＋4 phase of sleep,REMsleep ratio of nCPAP group improved in treatment group （P 〈0.05）.The QSQ score were higher in group nCPAP than before treatment and those in non treatment group （P 〈0.05）, which was lower than that in the control group （P 〈0.05）.Conclusion nCPAP treatment is effective for the patients with OSAHS,which could improve the short-term quality of life.