干预冠心病危险因素对冠状动脉病变的影响

The influence of risk factors for coronary heart disease intervention on coronary angiography during follow-up

目的：探讨干预冠心病危险因素对冠状动脉病变的影响。方法根据74例冠脉造影复查结果分为冠状动脉病变进展组（n ＝46）与无病变进展组（n ＝28），分析两组患者的临床资料及吸烟、高血压、高脂血症、糖尿病几项危险因素达标等情况。结果高血压（OR ＝13．51，95％CI：1．96-93．18）、高脂血症（OR ＝7．14，95％CI：1．39-36．75）和复查冠状动脉造影间隔时间长（OR ＝1．07，95％CI：1．02-1．11）是冠状动脉病变进展的危险因素，而复查间期危险因素减少（OR ＝0．04，95％CI：0．007-0．287）则可以降低病变进展的风险。结论干预冠心病危险因素达标有利于延缓冠状动脉病变的进展。

Objective To explore the influence of coronary angiography reexamination results of intervention for risk factors of coronary heart disease.Methods Seventy -four cases of coronary artery angiography reexamination were selected and divided into coronary artery lesion progression group （n =46）and no progression group （n =28）ac-cording to the results of coronary artery angiography,the difference of clinical data and smoking,hypertension,hyperlipi-demia,diabetes mellitus several risk factors of standard between two groups were compared.Results The hypertension （OR =13.51,95%CI：1.96 -93.18）,hyperlipidemia（OR =7.14,95%CI：1.39 -36.75）and long interval time of coro-nary artery angiography （OR =1.07,95%CI：1.02 -1.11）were risk factor of progression of coronary artery lesions.It can reduce the risk of disease progression by reduce risk factors （OR =0.04,95%CI：0.007 -0.287）.Conclusion The risk factors intervention for coronary heart disease can delay progression of coronary artery disease.