肿瘤化疗患者PICC致静脉炎形成的相关因素分析

Analysis of the Risk Factors for Phlebitis of Patients Treated with PICC Chemotherapy

目的分析经外周静脉置入的中心静脉导管(peripherally inserted central catheter,PICC)置管化疗和静脉炎的关联,探索发生原因和预防解决方案。方法对650例PICC置管化疗患者住院资料进行分析,以是否发生静脉炎为因变量,导管类型、白细胞计数、插管次数、外周静脉穿刺部位、导管末端静脉位置、导管留置时间为自变量,采用多元逐步回归分析静脉炎发生的影响因素。结果 PICC导管留置时间、插管次数、导管末端静脉位置和外周静脉置入部位是影响静脉炎发生的重要因素,其偏回归系数分别为-3.596、1.777、1.161和1.719(P<0.001)。结论 PICC置管的留置时间、技术操作、导管末端理想位置在预防静脉炎中有重要临床意义。

Objective To analyze the correlation between peripherally inserted central catheter （PICC） chemotherapy and the incidence of phlebitis, and to explore the causes and the methods of prevention and treatment. Methods The in-hospital data of 650 cases of PICC chemotherapy were recorded and calculated. Taking the incidence of phlebitis as dependent variable, and the catheter types, white blood cell count, times, peripheral vein puncture site, the place of the catheter end and the indwelling time multiple as the independent variables, the risk factors of phlebitis were analyzed by multiple stepwise regression method. Results The catheter indwelling time, times of intubation, the location of the catheter end, the location of the intubation in peripheral vein were the four major risk factors for phlebitis, with the partial regression coefficients being -3.596, 1.777, 1.161 and 1.719 respectively （P〈0.001）. Conclusion The PICC indwelling time, operating technique of PICC and an ideal location of the end of PICC have clinical significance in preventing phlebitis.