痫性发作在超早期脑梗死患者rt-PA溶栓预后的评估价值被引量：8

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摘要目的探讨痫性发作对接受静脉重组组织型纤溶酶原激活剂(rt-PA)溶栓治疗超早期脑梗死患者预后的临床评估价值。方法选取南华大学附属第一医院86例超早期脑梗死患者进行回顾性分析。所有患者均接受静脉rt-PA溶栓治疗,根据随访期转归分为患者预后结局良好组(观察组,n=34),患者预后结局不良组(对照组,n=52)。比较两组患者痫性发作率及经颅多普勒超声(TCD)检测值的差异,分析痫性发作与溶栓结局的相关性。结果与对照组比较,观察组患者的收缩期血流速度(Vs)、平均血流速度(Vm)、舒张期血流速度(Vd)明显较高,而搏动指数(PI)较低(P<0.05),且痫性发作率明显较高(P=0.006)。多元Logistic回归分析显示,痫性发作为患者预后结局的保护性因素。痫性发作为患者预后结局预测指标,灵敏度为35.29%,特异度为92.31%。结论静脉rt-PA溶栓治疗过程中出现痫性发作提示超早期脑梗死患者预后结局可能较好。

作者陈敏龙双祁彭超谢明

机构地区南华大学附属第一医院神经内科湖南省永州市中心医院心内科

出处《重庆医学》 CAS 北大核心 2016年第18期2538-2540,共3页 Chongqing medicine

基金湖南卫生计生委科研立项(B2015-55)

关键词脑梗死痫性发作重组组织型纤溶酶原激活剂溶栓治疗预后

分类号 R743.3 [医药卫生—神经病学与精神病学]

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