2011—2015年安顺市家畜口蹄疫免疫效果调查分析

Immune Effect Analysis of Livestock FMD Vaccine of Anshun during 2011—2015

为了解安顺市近5年家畜口蹄疫免疫效果,采用VP1结构蛋白抗体ELISA及液相阻断ELISA方法对全市家畜口蹄疫免疫血清进行免疫抗体监测。结果表明:2012、2013年猪O型口蹄疫合成肽疫苗抗体检测合格率极显著下降(P<0.01),2012年猪O型口蹄疫佐剂灭活疫苗及牛O型口蹄疫-亚洲Ⅰ型双价苗抗体检测合格率极显著下降(P<0.01);羊O型口蹄疫-亚洲Ⅰ型双价苗抗体检测合格率总体呈逐年上升趋势(P<0.01),猪O型口蹄疫合成肽疫苗比猪O型口蹄疫佐剂灭活疫苗保护率高。

In order to provide theoretical basis for vaccine selection and the establishment of immunization programs. Livestock foot and mouth disease vaccine （ FMDV） immune effect in Anshun in recent 5 years was evaluated. Methods of VP1 antibody ELISA and liquid phase blocking ELISA were used to detect immune antibody of livestock in Anshun. The result showed that：The qualified rate of antibody of O-type synthetic peptide FDMV in swine was slightly decreased in 2012 and 2013 （ P〈0.01 ）;the qualified rate of antibody of O-type inactivated FMDV in swine and O-type FMDV-AsiaⅠbivalent vaccine in bovine decreased slightly in 2012 （ P〈0.01 ）;O-type FMDV - AsiaⅠbivalent vaccine antibody pass-rate was increasing year by year in goat（ P〈0.01）;O-type synthetic peptide FDMV protection rate higher than O-type inactivated FMDV in swine.