摘要
目的了解南充市顺庆区1-15岁健康儿童麻疹、脊髓灰质炎(脊灰)抗体水平,评价免疫效果,为免疫规划工作提供科学依据。方法采用多阶段随机抽样方法采集1-15岁健康儿童手指末梢血13 020份,用酶联免疫吸附实验法(ELISA)检测麻疹、脊灰Ig G抗体。结果在检测的13 020份样本中,麻疹Ig G抗体阳性率95.03%,脊灰Ig G抗体阳性率95.99%;不同性别儿童麻疹、脊灰抗体阳性率差异无统计学意义(χ2=0.65、χ2=0.37,P〉0.05);不同年龄儿童麻疹、脊灰抗体阳性率差异有统计学意义(χ2=36.31、χ2=87.20,P〈0.01);城镇与农村儿童麻疹、脊灰抗体阳性率差异有统计学意义(χ2=683.34、χ2=563.91,P〈0.01)。结论顺庆区1-15岁健康儿童具有较高的麻疹、脊灰抗体水平,但城市与农村地区有显著差异,城市儿童麻疹、脊灰抗体水平显著高于农村儿童。
Objective To understand the antibody levels of measles and polio among healthy children aged 1-15 years in Shunqing district of Nanchong city,to evaluate the effect of immunization,and provide scientific basis for immune programming work. Methods ELISA was used for detection of measles Ig G and polio Ig G. Results A total of 13 020 blood samples were detected,the positive rate of measles Ig G and polio Ig G was 95. 03% and95. 99%,respectively. On gender,the difference of Ig G antibody positive rate of measles cases and polio cases were not statistically significant( χ2= 0. 65,χ2= 0. 37,P〈0. 05); as to different age groups,the difference of Ig G antibody positive rate of measles cases and polio cases were all statistically significant( χ2= 36. 31,χ2=87. 20,P〈0. 01); and for urban and rural area,the difference of Ig G antibody positive rate of measles cases and polio cases were all statistically significant( χ2= 683. 34,χ2= 563. 91,P〈0. 01). Conclusion The 1-15year-old children in Shunqing district have high immune antibody levels to measles and polio. Antibody levels of urban children against measles and polio antibody level is higher than rural children.
出处
《预防医学情报杂志》
CAS
2016年第6期607-610,共4页
Journal of Preventive Medicine Information
关键词
儿童
麻疹
脊髓灰质炎
抗体水平
children
measles
poliomyelitis
antibody level