杜洛克病理皮肤组织结构观察及研究

Observation of Pathological Skin Structure of Duroc Piglet

阿拉尔十二团万头猪场一头新生仔猪发生一起皮肤病变,表现为背臀部皮肤不同程度白斑、脱屑、脱毛、结痂等现象。为了探究引起杜洛克背臀部皮肤病变的可能原因,手术切取背臀部病变部位皮肤并制作成石蜡切片,皮肤切片经苏木精-伊红染色(HE染色)后用于显微镜观察,分析病理皮肤组织结构变化。显微镜下观察表皮角质层变薄,棘细胞层增宽,表皮突变宽或向下延伸。真皮网状层胶原纤维排列不整齐,走向凌乱且结构不清晰,皮肤附属器减少或萎缩,有炎性细胞浸润,血管腔增大内含大量红细胞。本病疑似基底细胞癌早期,确诊此病还需要做更进一步的研究。

The dorsal hip skin of a newborn Duroc pigpet expressed varying degrees of white spots, scaling, hair loss, crusting, etc. In oder to find the reason of skin lesions, the pathological skin was cut and made into paraffin sections. The sections were stained by HE staining and observed with mi- croscopy. The differences between the pathological and the normal skin structure were analyzed .The result showed that stratum corneum was thinner than the normal, prickle cell layer hypertrophier, epidermal mutation became wider or longer. Collagen fibers in dermal layer arranged irregularly, a- ligned massively and the structure was not clear. Skin adenexal atrophied and lumen became bigger, in which contained a large number of red blood cells. This disease was suspected the earlybasal cell carcinoma, but it is need to do further study if we want to diagnose correctly.