摘要
肾移植是治疗各种终末期肾病的有效手段。临床证实,应用脑死亡捐献(DBD)供肾移植的疗效比活体供肾差。重视对在体和离体DBD供肾的保护,减轻其热缺血、冷灌注、冷储存和再灌注损伤,改善DBD供肾活力,是研究的热点。本文主要综述DBD供肾的保护研究。
Renal transplantation is an effective method for a variety of end-stage renal disease treatment.It is known that the clinical outcome in kidney transplantation from living donors is superior to that for transplantation from brain dead donors(DBD).Effective measures should be adopted to reduce inflammation,warm/cold ischemia injury,and ischemia-reperfusion injury,in order to improve the DBD kidneys quality.We reviewed the current protective research of DBD kidneys.
出处
《武汉大学学报(医学版)》
CAS
2016年第4期586-591,611,共7页
Medical Journal of Wuhan University
关键词
脑死亡器官捐献
肾移植
器官保存
Donation After Brain Death
Renal Transplantation
Organ Preservation