压力目标P值在重度功能性便秘生物反馈训练治疗中的作用

The effect of pressure target P value in the biological feedback training treatment of severe functional constipation

目的探讨不同压力P值在重度功能性便秘生物反馈训练中的作用。方法 2012年4月—2014年10月选择在浙江省立同德医院诊断治疗的重度功能性便秘患者120例。按照压力目标P值(P1=10 mm Hg,P2=25mm Hg,P3=35 mm Hg)不同,分为3组,各40例。采用压力介导生物反馈训练,10次为1个疗程,3组患者治疗3个疗程。记录3组患者临床疗效,直肠压力测定以及结肠通过试验测定结果。结果 P1组总有效率为50.00%,P2组总有效率为77.50%,P3组总有效率为40.00%,P2组显著优于P1及P3组,差异有统计学意义(P<0.05)。直肠压力测定显示,治疗前3组患者的肛管静息压、缩榨压、排便压差异无统计学意义(P>0.05),治疗后P2组患者肛管静息压、缩榨压、排便压均高于P1组、P3组,P2组排便压高于P1组,差异均具有统计学意义(P<0.05)。结肠通过试验显示,治疗前3组患者的排出粒数、排出率差异无统计学意义(P>0.05);治疗后P2组患者排出粒数、排出率均高于P1组、P3组,P2组排出粒数、排出率高于P1组,差异均具有统计学意义(P<0.05)。结论生物反馈治疗功能性便秘疗效较为肯定,且在压力P值为25 mm Hg时患者的临床疗效最显著,且直肠压力、结肠通过试验结果最佳,值得临床推广应用。

Objective To investigate the effect of different values of the pressure P in poisoning functional constipation biofeedback training. Methods From April,2012 to October,2014,120 cases of patients with functional constipation in severe hospital diagnosis and treatment were selected. According to the pressure target P value（ P1 = 10 mm Hg,P2 = 25 mm Hg,P3 = 35 mm Hg）,divided into three groups,each 40 cases. Using pressure-mediated biofeedback training,ten times as a course of treatment,three groups of patients three courses. Clinical efficacy record three groups of patients,colon rectal pressure measurement results measured by experiment and. Results The results showed that,in P1 group,the total efficiency was 50. 00%,in P2 group,the total effectiveness was 77. 50%,in P3 group,the total efficiency was 40. 00%,the P2 group was significantly better than the P1 and P3 groups,the difference was statistically significant（ P〈0. 05）. Rectal pressure measurement show that in the first treatment,the three groups of patients anal resting pressure,reduced pressing pressure,bowel pressure was not statistically significant（ P〈0. 05）,after treatment,P2 patients anal resting pressure,reduced pressing pressure,defecation Pressure group were higher than P1,P3 groups,P2 group defecation pressure higher than P1 group,the differences were statistically significant（ P〈0. 05）. Colon through trial showed that before treatment,the number of cases discharged three groups of patients,the discharge rate was not statistically significant（ P〈0. 05）,after treatment,P2 number of cases of patients discharged,the discharge rate is higher than P1 group,P3 group,P2 group discharge number of cases,the discharge rate is higher than P1 group,the differences were statistically significant（ P〈0. 05）. Conclusion In summary,biofeedback in the treatment of functional constipation curative effect is sure and in pressure P value is 25 mm Hg,the clinical efficacy in patients with the most significant and pressure of rectum and colon by experimental results,and the best,it is worth of clinical application.