小头畸形的临床诊断与细胞和分子生物学诊断的研究进展

Research progress of clinical,cellular and molecular biology diagnosis of microcephaly

小头畸形是儿科常见的神经系统畸形,尤其在智力低下的儿童中更常见。迄今为止国内对小头畸形的相关研究报道较少,本文通过复习国外相关文献,对小头畸形的临床诊断与细胞和分子生物学诊断进行综述,旨在为小头畸形的临床诊治及进一步研究提供参考。

Microcephaly is a common nervous system malformation in pediatric outpatients,especially in children with mental retardation.Till now,only a few domestic researches reported about microcephaly.This paper reviews the researches reported abroad about clinical,cellular and molecular biology diagnosis of microcephaly,in order to provide references for clinical diagnosis,treatment and further researches.