缬沙坦联合贝那普利治疗糖尿病肾病的临床研究

Valsartan combined shell that split clinical research for the treatment of diabetic nephropathy

目的：研究分析缬沙坦联合贝那普利在糖尿病肾病治疗中的应用效果。方法：选取2013年10月～2015年4月本院收治的60例糖尿病肾病病例作为主要的研究对象,通过随机数字表法随机分为参照组以及分析组,分析组使用缬沙坦与贝那普利联合治疗,参照组使用贝那普利进行治疗,对两组治疗效果以及其并发症发生情况进行分析对比。结果：参照组治疗总有效率为60.00%,分析组治疗总有效率为86.67%,参照组治疗总有效率明显低于分析组,两者差异显著,具有统计学意义（P〈0.05）。参照组并发症发生率为13.33%,分析组并发症发生率为3.33%,参照组并发症发生率明显高于分析组,两者差异显著,具有统计学意义（P〈0.05）。结论：在糖尿病肾病治疗过程中,使用缬沙坦与贝那普利联合治疗,可以有效提升治疗效果,同时降低并发症发生率,值得进一步推广使用。

Objective：to study the analysis of valsartan combined bei the application effect of captopril in the treatment of diabetic nephropathy.Selection methods：in October 2013 to April 2015 in our hospital during the period of 60 cases of diabetic nephropathy patients treated as the main research object,through the stochastic indicator method patients were randomly divided into control group and group analysis,analysis of group of patients with valsartan and shellfish that captopril combined treatment,control group is used that captopril treatment,treatment effect of two groups of patients and the comparative analysis its complications.Results：the total effective rate of control group patients was 60.00%,analysis of the group of patients treatment the total effective rate was 86.67%,the total effective rate of control group patients was lower than that in group analysis of patients with significant difference between them,and has significant statistical significance（P〈 0.05）.The complication rate of control group was 13.33%,the analysis group,incidence of complications was 3.33%,the complication rate of control group is significantly higher than analysis group,significant difference between them,and has significant statistical significance（P〈 0.05）.Conclusion：in the process of diabetic nephropathy therapy,the use of valsartan and shellfish that captopril combined treatment,can effectively improve the treatment effect of patients,and the complication rate of the patient at the same time,further promote the use.