老年高脂血症患者肝功能酶学指标变化研究

Study on the chances of liver function enzymes index in elder population with hyperlipidemia

目的探讨江苏省患高脂血症老年人群的肝功能酶学指标变化特点及患脂肪肝几率,为研究老年人疾病变化特点、实现老年人易患病的经济监测提供依据。方法对高脂血症和健康老年人组,分别进行血清学肝功能酶学项目、患脂肪肝情况的检验分析。结果实验组丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)和γ-谷氨酰基转移酶(GGT)检测结果均高于对照组,差异有统计学意义(P<0.01);实验组患脂肪肝人数显著高于对照组;实验组中男性肝功能酶学指标异常率高于女性。结论高血脂症老年人更易患脂肪肝,可首选AST、ALT、GGT作为肝功能监测指标,患高脂血症的男性老人肝功能酶学指标变化更为明显。

Objective To study the changes of liver function enzymes and occurance rate of fatty liver for elder patients with hyperlipidemia,so as to provide basis for studying the changes of incidence and the economic monitoring for the elderly. Methods Hyperlipidemia and healthy old people were conducted for the change of serum liver enzymes and for the detection and analysis of fatty liver. Results The serum alanine aminotransferase（ ALT）,aspartate aminotransferase（ AST） and glutamine acyltransferase（ gamma- GT） test results of hyperlipidemia group were significantly higher than the control group,with the differences statistically significant（ P〈0. 01）. The number of fatty liver in the experimental group was significantly higher than that in the control group. The abnormal rate of liver function in the experimental group was higher than that in the female. Conclusion Elderly people with hyperlipidemia are more likely to suffer from fatty liver. AST,ALT,GGT can be primarily selected as the monitoring indicators of liver function,so the liver function enzymes factors of male elderly patients with hyperlipidemia is more obvious.