江西省南昌市一例输入性卵形疟病例报告

An imported case of Plasmodium ovale infection in Nanchang City of Jiangxi Province

本文报道了1例非洲输入性卵形疟的诊断、调查、治疗过程。患者为非洲尼日利亚务工返乡人员,回国后1周因发热、头疼等症状就医。血膜镜检见多期卵形疟原虫,环状体核较大,裂殖体、配子体期棕黄色疟色素较粗大;受染红细胞明显变形,呈多种不规则形态,具备卵形疟原虫特点。巢氏PCR基因检测产物约800 bp大小,与卵形疟相符。对患者用氯喹加伯氨喹8日疗法正规治疗后好转出院。

The process of diagnosis,epidemiological survey and treatment of an imported ovale malaria patient wasreported in this paper. The patient had worked in Nigeria,Africa and received the medical treatment for fever,headaches andother symptoms after he returned home one week later. Some classic characteristics of Plasmodium ovale, including multiplestages of protozoa,thick ring forms,thick granules of malaria pigment in the schizont stage and gametocyte stage were found inhis blood smear. In addition,the infected RBC showed irregular shape due to its obvious deformation. The genetic testing withnested PCR indicated that the amplified fragment was size of 800 bp,which also belongs to the characteristics of P. ovale. Thepatient received the standard treatment with chloroquine/primaquine,and finally he was cured and discharged after 8- dayhospitalization.