妊娠期高血压疾病孕妇子宫动脉多普勒血流监测的临床价值

Clinical value of uterine artery blood flow monitoring for women with hypertensive disorder complicating pregnancy by Doppler ultrasound

目的探讨妊娠期高血压疾病(HDCP)孕妇晚期子宫动脉多普勒血流监测变化及临床意义。方法选取2014年1-12月该院收治的妊娠晚期HDCP孕妇100例作为HDCP组,另选取同期正常健康孕妇98例作为对照组。于分娩前1周内行彩色多普勒超声检测孕妇子宫动脉的阻力指数(RI)及收缩期峰值血流速度与舒张末期血流速度的比值(S/D)。比较两组孕妇子宫动脉血流阻力指标变化,新生儿1min和5min的Apgar评分及出生体重。结果 HDCP组孕妇子宫动脉阻力指标明显高于对照组孕妇;HDCP胎儿生长发育受限,普遍存在缺氧现象,与对照组比较,差异均有统计学意义(P<0.05)。结论彩色多普勒超声检测能观察HDCP孕妇子宫动脉血流变化,对预测孕妇HDCP的发生及评估胎儿宫内状态具有一定的临床应用价值。

Objective To explore the changes of uterine artery blood flow monitoring in hypertensive disorder complicating pregnancy （HDCP） patients during the.third trimester of pregnancy and the clinical significance. Methods A total of 100 HDCP women during the third trimester of pregnancy in the hospital from January to December in 2014 were enrolled as HDCP group, and 98 healthy pregnant women during the same period were selected as control group. One week before delivery, color Doppler uhrasonography was used to determine uter- ine artery resistance index （RI） and the ratio of peak systolic velocity to end diastolic velocity （S/D） . The changes of resistant indexes, Apgar score at 1 minute and 5 minutes, and birth weight were compared between the two groups. Results Uterine artery resistance indexes in HDCP group were significantly higher than those in control group; the fetuses in HDCP group had growth and developmental restriction with universal hypoxia, there was statistically significant difference compared with control group （P〈0. 05 ） . Conclusion Color Doppler uhrasonography can observe the changes of uterine artery blood flow for HDCP women, that shows a certain value in predicting occurrence of HDCP and assessing fetal intrauterine status.