甲钴胺联合硫辛酸治疗糖尿病周围神经病变的疗效探讨

Curative Effect Observation on Mecobalamine Combined with Lipoic Acid in Treatment of Diabetic Peripheral Neuropathy

目的探讨甲钴胺联合硫辛酸治疗糖尿病周围神经病变的疗效。方法从2013年3月—2015年9月该院收治的患者中方便选出110例,将其分为两个小组,每组患者55例。对其中一组单纯采用甲钴胺进行治疗,作为对比组;对另外一组患者则采用甲钴胺联合硫辛酸治疗,作为研究组。分别记录两组患者临床治疗效果和神经传导速度的影响情况。结果研究组治疗有效率为92.73%(51/55),明显高于对比组72.73%(40/55)(P<0.05)。同时两组患者治疗后神经传导速度明显高于治疗前,其中研究组传导速度较快(P<0.05)。结论采用甲钴胺联合硫辛酸治疗方法效果突出,能够改善神经传导速度。

Objective To discuss the curative effect of mecobalamine combined with lipoic acid in treatment of diabetic peripheral neuropathy. Methods 110 cases of patients admitted and treated in our hospital from March 2013 to September 2015 were selected and divided into two groups with 55 cases in each, the control group were treated with simple meeobalamine, the research group were treated with mecobalamine combined with lipoie acid, the clinical treatment effects and effects of nerve conduction velocity of the two groups were respectively recorded. Results The treatment effective rate in the research group was obviously higher than that in the control group, [92.73% （51/55） vs 72.73% （40/55）], P〈0.05, at the same time, the nerve conduction velocity of the two groups after treatment was obviously higher than that before treatment, and the nerve conduction velocity of the research group was faster, P〈0.05. Conclusion The treatment effect of meeobalamine combined with lipoic acid is prominent, which can improve the nerve conduction velocity.