H型高血压患者血清Hcy、Cyst-C、UA水平与颈动脉粥样硬化的关系

Correlation between Serum Hcy, Cyst-C and UA Levels in Patients with Htype Hypertension and Carotid Atherosclerosis

目的探究H型高血压患者颈动脉粥样硬化与血清Hcy、Cyst-C、UA水平的关系。方法方便选取2013年1月—2014年1月于该院治疗的88例H型高血压患者,分为观察组和对照组2组,每组44人,前者超声检查颈动脉内膜中层厚度(IMT)正常,后者IMT明显增厚,观察两组间血清Hcy、Cyst-C、UA水平指标差异。结果观察组血清Hcy、Cyst-C、UA指标显著高于对照组(P<0.05),上述指标为IMT独立危险因素,IMT与其明显相关(r=0.28、0.33、0.27,P<0.05)。结论 H型高血压患者血清Hcy、Cyst-C、UA水平与颈动脉粥样硬化明显相关,可成为其早期诊断指标。

Objective To research the correlation between serum Hcy, Cyst-C and UA levels in patients with H-type hy- pertension and carotid atherosclerosis. Methods 88 cases of patients with H-type hypertension treated in our hospital from January 2013 to January 2014 were divided into two groups with 44 cases in each, the IMT of the former was normal after ultrasonic examination, the IMT of the latter was obviously thickened, and the differences in the indexes of serum Hcy, Cyst-C and UA levels between the two groups were observed. Results The serum Hcy, Cyst-C and UA indexes in the ob- servation group were obviously higher than those in the control group（P〈0.05）, the above indexes were the independent risk factors of IMT, and the IMT was obviously correlated with them（r=0.28, 0.33, 0.27, P〈0.05）. Conclusion The serum Hcy, Cyst-C and UA levels in patients with H-type hypertension were obviously correlated with carotid atherosclerosis, which can be the early diagnostic indexes.