胎儿染色体产前诊断临床分析

Clinical Analysis of Prenatal Diagnosis of Fetal Chromosome

目的探讨胎儿染色体分析在产前诊断中的价值。方法选取2010年1月—2015年8月在该医院进行胎儿染色体产前诊断的198例孕妇,对脐带血进行核型分析。结果 198例孕妇中染色体异常检出率为11.6%,其中染色体数目异常16例,染色体结构异常7例,脐带穿刺并发症发生率为2.5%。结论对胎儿进行染色体分析在产前诊断中的意义重大,可以明显提高新生儿的健康质量,值得在临床上广泛应用。

Objective To discuss the value of fetal chromosome analysis in the prenatal diagnosis. Methods 198 cases of pregnant women receiving prenatal diagnosis of fetal chromosome in our hospital from January 2010 to August 2015 were selected, and their cord blood was given karyotype analysis. Results In the 198 cases, the detection rate of chromosome ab- normalities was 11.6%, among them, the chromosome numerical abnormalities occurred to 16 cases, chromosome structural abnormalities occurred to 7 cases, the incidence rate of the complication such as cordocentesis was 2.5%. Condusion The fetal chromosome analysis in the prenatal diagnosis is of great significance in the prenatal diagnosis, which can obviously improve the health quality of newborns, and it is worth wide application in clinic.