降压药物在老年高血压病人中的药学特点分析

Analysis of Pharmaceutic Characteristics of Antihypertensive Drugs in Elderly Patients with Hypertension

目的探讨降压药物在老年高血压病人中的药学特点。方法方便选择2015年1月—2016年1月该院收治的120例老年高血压病人,观察分析该组患者降压药物的应用类型、不良反应与血压达标情况。结果该组120例患者中服用缬沙坦42例血压达标率为78.57%、卡托普利72.42%、美托洛尔71.43%、络活喜68.00%、贝那普利66.67%、吲达帕胺66.67%、呋塞米50.00%。该组120例患者中舒张压达标率为85.00%,高于收缩压的70.83%。该组老年高血压用药所致不良反应中以贝那普利(33.33%)最高。结论降压药物对老年高血压病人舒张压的降压效果优于收缩压,临床应根据患者血压水平及时调整药物用量,以此保证用药的疗效与安全性。

Objective To discuss the pharmaceutic characteristics of antihypertensive drugs in elderly patients with hypertension. Methods 120 cases of elderly patients with hypertension admitted and treated in our hospital from January 2015 to January 2016 were selected, and the application types, adverse reactions and blood pressure standard situations of the patients were observed and analyzed. Results In the 120 cases of patients, the blood pressure standard rates of 42 cases taking valsartan, 29 cases taking captopril, 7 cases taking metoprolol, 25 cases taking amlodipine besylate tablets, 12 cases taking benazepril, 3 cases taking indapamide and 2 cases taking furosemide were respectively 78.57%, 72.42%, 71.43%,68.00%, 66.67%, 66.67% and 50.00%, the standard rate of diastolic pressure of the 120 cases of patients was higher than that of systolic pressure,（85.00% vs 70.83%） and in this group, the incidence rate of adverse reactions caused by benazepril was the highest, which was 3.33%. Conclusion For elderly patients with hypertension, the hypotensive effect of hypotensive drugs for the diastolic pressure is better than that of hypotensive drugs for the systolic pressure, and we should timely adjust the drug dose according to the patient’s blood pressure level thus ensuring the curative effect and safety of medication.