小蓟止血汤加减治疗IgA肾病单纯血尿疗效分析

Observation on Curative Effect of Modified Xiaoji Zhixue Decoction in Treatment of Simple Hematuria IgA Kidney Disease

目的探讨小蓟止血汤加减治疗IgA肾病单纯血尿的临床疗效。方法随机选取2013年9月—2015年10月该院收治IgA肾病单纯血尿患者70例,随机分为对照组和观察组。对照组35例患者,给予泼尼松龙片和双嘧达莫片治疗;观察组35例患者则在对照组的基础上,加用小蓟止血汤加减治疗。观察分析两组疗效。结果观察组的总有效率为91.43%,明显高于对照组的65.71%,差异有统计学意义(P<0.01),可见观察组疗效优于对照组。结论小蓟止血汤加减对于单纯血尿型IgA肾病疗效显著,可有效缓解血尿症状,临床治愈率远高于单纯的西药治疗,且安全性高,无毒副作用,具有较高的临床应用价值。

Objective To observe the clinical curative effect of modified xiaoji zhixue decoction in treatment of simple hematuria IgA kidney disease. Methods 70 cases of patients with simple hematuria IgA kidney disease admitted and treated in our hospital from September 2013 to October 2015 were selected and randomly divided into two groups with 35 cases in each, the control group were treated with prednisone tablet and dipyridamole tablet, the observation group were treated with additional modified xiaoji zhixue decoction on the basis of the control group, and the curative effects of the two groups were observed and analyzed. Results The total effective rate in the observation group was obviously higher that in the control group, and the difference had statistical significance,（91.43% vs 65.71%）, P〈0.01, and the curative effect in the observation group was better than that in the control group. Conclusion The curative effect of modified xiaoji zhixue decoction in treatment of simple hematuria IgA kidney disease is obvious, which can effectively relieve the hematuria symptoms, and the clinical cure rate is much higher than the simple western medicine treatment with high safety and without side and toxic effects, and it is of higher clinical application value.