应用退热贴穴位贴敷治疗输入cik细胞发热临床研究

Clinical Research on Defervescence Acupoint Sticking Therapy of Fever Caused by the Transfusion of Cytokine-induced Killer Cell

目的探讨应用退热贴穴位贴敷治疗输入cik细胞产生发热症状患者的临床效果。方法整群选取2014年5月—2015年6月间该院收治的行cik细胞输入治疗后产生发热症状的肺癌患者共114例,将其以数字随机分组的形式均分为实验组及对照组两组,每组57例,其中给予实验组患者退热贴穴位贴敷进行护理干预,给予对照组患者布洛芬混悬液进行护理干预,对比观察两组患者退热效果及其它相关指标变化情况。结果经护理措施干预后实验组患者显效46例(80.7%),有效10例(17.5%),无效1例(1.8%),总有效率为(98.2%),对照组患者显效34例(59.6%),有效11例(19.3%),无效12例(21.1%),总有效率为(78.9%),两组对比,实验组患者退热总有效率明显高于对照组患者,差异有统计学意义(P<0.05);护理措施干预后实验组患者出现3例(5.3%)皮肤瘙痒等不良反应,对照组患者出现10例(17.5%)出现呕吐、恶心等胃肠道症状,两组对比,实验组患者不良反应出现情况明显优于对照组患者,差异有统计学意义(P<0.05)。结论应用退热贴穴位贴敷护理治疗输入cik细胞产生发热症状的肺癌患者临床效果较好,且不良反应出现情况明显较低,值得于临床中进一步推广使用。

Objective To discuss the clinical effect of defervescence acupoint sticking therapy of patients with fever symptom caused by the transfusion of cytokine-induced killer cell. Methods 114 cases of lung cancer patients with fever symptom after the transfusion of cytokine-induced killer cell admitted and treated in our hospital from May 2014 to June 2015 were selected and randomly divided into two groups with 57 cases in each, the experimental group were given the defervescence acupoint sticking therapy for nursing intervention, the control group were given the ibuprofen suspension for nursing intervention, and the defervescence effect and changes of other relevant indexes of the two groups were compared and observed. Results After nursing intervention, in the experimental group, 46 cases were markedly effective（80.7%）, 10 cases were effective（17.5%）, 1 case was ineffective（1.8%） and the total effective rate was 98.2%, in the control group, 34 cases were markedly effective（59.6%）, 11 cases were effective（17.5%）, 12 cases were ineffective（21.1%）, and the total effective rate was 78.9%, and the total effective rate of defervescence in the experimental group was obviously higher than that in the control group and the difference had statistical significance, P〈0.05; after nursing intervention, the adverse reactions such as skin itch occurred to 3 cases（5.3%） in the experimental group, the adverse reactions such as vomiting, nausea and other gastrointestinal tract symptoms occurred to 10 cases（17.5%） in the control group, and the occurrence of adverse reactions in the experimental group was obviously better than that in the control group by comparison, and the difference had statistical significance, P〈0.05. Conclusion The clinical effect of defervescence acupoint sticking nursing therapy of lung cancer patients with fever symptom caused by the transfusion of cytokine-induced killer cell is better, and the incidence rate of adverse reactions is low, which is worth clinical further promotion and application.