两种不同输血方式对择期行脊柱椎间融合器植入植骨融合术患者的影响研究

Research on Effect of Two Different Transfusion Methods on Patients with Selective Bone Graft Fusion Implanted with Spine Interbody Fusion Cage

目的研究择期行脊柱椎间融合器植入植骨融合术患者采用两种不同输血方式对患者的影响。方法方便选取60例该院2013年6月—2015年8月期间行脊柱椎间融合器植入植骨融合术的患者,将所有患者按随机数字表法分为两组各30例。其中30例患者术中采用自体输血方式进行输血作为自体输血组;另30例患者术中采用异体输血方式进行输血作为异体输血组。观察两组患者手术情况、血常规情况以及不良反应情况等。结果自体输血组术中输液量、术中出血量均大于异体输血组,治疗费用明显低于异体输血组(P<0.05)。术后自体输血组RBC、PLT以及Hb均大于异体输血组,WBC小于异体输血组(P<0.05)。两组患者不良反应包括过敏反应、荨麻疹以及非溶血性发热等,自体输血组、异体输血组发生率分别为13.33%、26.67%,自体输血组明显较低(P<0.05)。结论自体输血可进一步降低输血不良反应,提高血红蛋白及红细胞,在大量输血情况下尤为适用,值得临床应用及推广。

Objective To research the effect of two different transfusion methods on patients with selective bone graft fusion implanted with spine interbody fusion cage. Methods 60 cases of patients with selective bone graft fusion implanted with spine interbody fusion cage treated in our hospital from June 2013 to August 2015 were selected and randomly divided into two groups, 30 cases of patients adopting the autologous blood transfusion method in operation were selected as the autologous blood transfusion group, 30 cases of patients adopting the allogeneic blood transfusion method in operation were selected as the allogeneic blood transfusion group, and the operation conditions, blood routine conditions and adverse reactions of the two groups were observed. Results The intraoperative transfusion volume and intraoperative blood loss in the autologous blood transfusion group were more than those in the allogeneic blood transfusion group, the treatment cost in the autologous blood transfusion group was obviously lower than that in the allogeneic blood transfusion group（P〈0.05）, the RBC, PL and Hb in the autologous blood transfusion group after operation were more than those in the allogeneic blood transfusion group,WBC in the autologous blood transfusion group was less than that in the allogeneic blood transfusion group（P〈0.05）, the adverse reactions of the two groups included anaphylactic reaction, urticarial and febrile non hemolytic transfusion, the incidence rate of adverse reactions in the autologous blood transfusion group was obviously lower than that in the allogeneic blood transfusion group,（13.33% vs 26.67%）（P〈0.05）. Conclusion Autologous blood transfusion can further reduce the blood transfusion adverse reactions and improve the hemoglobin and erythrocyte, and it is especially applicable in the case of massive blood transfusion, which is worth clinical application and promotion.