调节肠道微生态疗法在肝硬化自发性腹膜炎治疗中的作用

Effect of Regulation of Gut Microbial Ecology Therapy in Treatment of Spontaneous Peritonitis in Cirrhosis

目的研究调节肠道微生态疗法在肝硬化自发性腹膜炎中的作用。方法整群选取该院收治的102例肝硬化自发性腹膜炎患者为研究对象,随机分观察组与对照组均51例,观察组:乳果糖口服溶液联合培菲康胶囊治疗,对照组常规抗生素治疗,对比相关指标。结果观察组治疗有效率(92.6%)、临床症状消失时间均高于对照组。治疗后观察组肝功能指标ALT、AST、STB均低于对照组(P<0.05)。结论调节肠道微生态疗法疗效显著,加快患者各症状的消失时间,对各项肝功能也有良好的控制作用。

Objective To research the effect of regulation of gut microbial ecology therapy in treatment of spontaneous peritonitis in cirrhosis. Methods 102 cases of patients with spontaneous peritonitis in cirrhosis treated in our hospital were selected as the research objects and randomly divided into two groups with 51 cases in each, the observation group were treated with lactulose oral solution combined with bifid triple viable capsules, the control group were treated with conventional antibiotic, and the relevant indexes were compared. Results The treatment effective rate in the observation group was92.6%, and the disappearance time of clinical symptoms and treatment effective rate in the observation group were higher than those in the control group, after treatment, the indicators of liver function including ALT, AST and STB in the observation group were lower than those in the control group（P〈0.05）. Conclusion The curative effect of regulation of gut microbial ecology therapy is obvious, which can speed up the disappearance time of various symptoms and has a good controlling effect on various liver functions.