抗生素管理及手卫生对新生儿细菌感染的影响

The Effect of Antibiotic Administration and Hand Hygiene on Neonatal Bacterial Infection

目的探讨抗生素管理及手卫生对新生儿细菌感染的影响。方法选取2013年1月—2015年12月期间实施抗生素和手卫生管理的细菌感染新生儿(110例)作为观察组,同时选取管理前的细菌感染的新生儿(122例)作为对照组,并比较两组患儿抗生素使用强度、CRE检出率以及医务人员手卫生依从性。结果观察组患者抗生素使用强度以及CRE检测率明显低于对照组(P<0.05),而且实施管理后医务人员手卫生依从性明显高于管理前(P<0.05)。结论加强抗生素和手卫生管理可有效降低抗菌药物使用轻度,减少新生患儿CRE感染比例,提高医务人员手卫生依从性。

Objective To explore the effect of antibiotic administration and hand hygiene on neonatal bacterial infection. Methods January 2015 2013 to December 2006 the implementation of antibiotics and hand hygiene management of bacteri-al infection in neonates（n=110） as observation group, and selected the former management of bacterial infection in neonates （122 cases） as the control group and compared between the two groups of children with antibiotic use intensity, CRE detec-tion rate and medical personnel hand hygiene compliance. Results in the observation group, the use of antibiotics and CRE detection rate was significantly lower than that of the control group （P〈 0.05）, and the implementation of the management of medical staff hand hygiene compliance was significantly higher than that before management （P 〈 0.05）. Conclusion strengthening the management of antibiotics and hand hygiene can effectively reduce the use of antibiotics and reduce the proportion of CRE infection in newborn infants and improve the hand hygiene compliance of medical staff.