抗结核治疗对菌阴肺结核合并非小细胞肺癌患者生命质量管理的影响

The Influence of Anti-tuberculosis Treatment on Life Quality of Pulmonary Tuberculosis Negative Combine the Non-small Cell Lung Cancer Patients

目的研究抗结核治疗对菌阴肺结核合并非小细胞肺癌(NSCLC)患者生命质量的影响。方法回顾性分析2012年1月—2014年8月,于保定市第三医院肺二科确诊肺结核合并NSCLC且上痰抗酸杆菌阴性、资料完整者82例,抗结核治疗者42例作为研究组(A组),未抗结核治疗者40例作为对照组(B组)。分别于确诊初期和抗结核治疗3月时行FACT-L评分,探讨两组患者治疗前后的生命质量变化情况。结果经过3个月的治疗,A组死亡3例,B组死亡4例,A组患者在生理状况、社会/家庭状况、情感状况功能状况等方面有所改善,与治疗前比较差异有统计学意义(P<0.05),而B组生命质量各方面改善不明显,甚至有所恶化。结论抗结核治疗可以改善菌阴肺结核合并非小细胞肺癌患者生命质量。

Objective To explore the effect of anti-tuberculosis treatment on life quality of pulmonary tuberculosis negative combine the non-small cell lung cancer patients.Methods Retrospectively analyzed the clinical data of 82 Pulmonary Tuberculosis Negative Combine the non-small cell lung cancer patients.42 cases were set to research group and treated with anti-tuberculosis treatment,The other 42 cases were Set to control group znd without anti-tuberculosis treatment.Compare the change of the quality of life of two groups before and after treatment.Results After three months treatment,3 cases died of research group,and 4 of control group,A group of patients in physiology,social/family status,the respect such as emotional function conditions have improved,the situation of ？physiology,social/family status emotional function conditions of research group all imporved.Compared with before treatment,the difference was statistically significant（P〈0.05）.Conclusion Anti-tuberculosis treatment can improve life quality of pulmonary tuberculosis negative combine the non-small cell lung cancer patients.