关于多囊卵巢综合征中TGF-β表达与子宫内膜容受性关系的研究进展被引量：4

Research progress on association between TGF-βexpression and endometrial receptivity in patients with polycystic ovary syndrome

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摘要多囊卵巢综合征(PCOS)是一种以排卵障碍、高雄激素血症以及多囊卵巢为特征的病变。相关文献报道转化生长因子-β(TGF-β)是评价子宫内膜容受性的指标之一,本文将从TGF-β促进子宫内膜增生,在子宫内膜中呈周期性表达,参与雌孕激素调节等方面对TGF-β与子宫内膜容受性关系的研究现状进行综述,进一步探讨PCOS患者TGF-β表达异常是否影响子宫内膜容受性。 Polycystic ovary syndrome （PCOS） is a disease characterized by ovulation disorder, hyperandrogenism and polycystic ovary. TGF-β level is one of the indicators to evaluate endometrial receptivity. This review summarizes the research progress of TGF-β in promoting endometrial hyperplasia, cyclical expression in endometrium and regulating estrogen and progesterone to explore whether abnormal expression of TGF-β affects endometrial receptivity in PCOS patients.

作者和祯琳马艳萍

机构地区昆明理工大学医学院昆明理工大学附属昆华医院

出处《生殖医学杂志》 CAS 2016年第7期668-671,共4页 Journal of Reproductive Medicine

基金云南省应用基础研究重点项目(2013FZ262) 国家卫计委科技计划项目子项目(201402004)

关键词多囊卵巢综合征转化生长因子Β 子宫内膜容受性 Polycystic ovary syndrome （ PCOS）, Transforming growth factor β （ TGF-β ）,Endometrial receptivity

分类号 R [医药卫生]

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参考文献36

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