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胰腺神经内分泌肿瘤肝转移的治疗进展

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摘要 胰腺神经内分泌肿瘤(pancreatic neuroendocrine tumor,PNET)是一类少见的胰腺原发性肿瘤,占所有胰腺肿瘤的1%~2%^([1-2])。随着高分辨率影像技术的应用普及,PNET的检出率逐年升高。PNET可分为功能性及无功能性,功能性PNET(如胰岛素瘤、胃泌素瘤等)主要表现为激素过度分泌所致症状,而无功能性PNET早期缺乏典型的临床表现,
出处 《外科理论与实践》 2016年第3期273-276,共4页 Journal of Surgery Concepts & Practice
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  • 1LIU Hong ZHANG Su-zhan WU Yu-lian FANG He-qing LI Jiang-tao SHENG Hong-wei WANG Yong.Diagnosis and surgical treatment of pancreatic endocrine tumors in 36 patients:a single-center report[J].Chinese Medical Journal,2007(17):1487-1490. 被引量:11
  • 2Zoncu R,Efeyan A,Sabatini DM. mTOR:from growth signal integration to cancer,diabetes and ageing[J].Nature Reviews Molecular Cell Biology,2011.21-35.
  • 3Zinzalla V,Stracka D,Oppliger W. Activation of mTORC2 by association with the ribosome[J].Cell,2011.757-768.
  • 4Oh WJ,Wu CC,Kim SJ. mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Aktpolypeptide[J].EMBO Journal,2010.3939-3951.
  • 5Shende P,Plaisance I,Morandi C. Cardiac raptor ablation impairs adaptive hypertrophy,alters metabolic gene expression,and causes heart failure in mice[J].Circulation,2011.1073-1082.
  • 6Siedlecki AM,Jin X,Muslin AJ. Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure[J].Kidney International,2009.800-808.
  • 7Kemi O J,Ceci M,Wisloff U. Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy[J].Journal of Cellular Physiology,2008.316-321.
  • 8Zhang D,Contu R,Latronico MY. MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice[J].Journal of Clinical Investigation,2010.2805-2816.
  • 9Giordano A,Romano A. Inhibition of human in-stent restenosis:a molecular view[J].Curr Opin Pharmaco1,2011.372-377.
  • 10Weichhan T,Saemann MD. The multiple facets of mTOR in immunity[J].Trends in Immunology,2009.218-226.

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