炎性因子在2型糖尿病及非酒精性脂肪肝中的作用

The Role of Inflammatory Cytokines in Type 2 Diabetes Mellitus and Non-alcoholic Fatty Liver

随着社会生活水平的提高以及生活模式的现代化,2型糖尿病的人群数量在全球呈迅猛式增长;同时对2型糖尿病发病机制的研究也更加深入。2型糖尿病与炎性因子有因果关系,在内分泌科,2型糖尿病常常合并非酒精性脂肪性肝病,而非酒精性脂肪性肝病的发病机制也与炎性因子有关。该文从分子层次解释两种疾病相互依存的原因,以期为临床提供利用炎性因子作为预测疾病风险的依据。

With the improvement of living standards and modernization of social lifestyle, the number of people with type 2 diabetes in the world is rapidly growing. At the same time, the researches on the pathogenesis of type 2 diabetes are also more in-depth, and studies have shown that there is a causal relationship between type 2 diabetes and inflammatory cytokines. Furthermore, in endocrinology, type 2 diabetes often merges another disease-nonalcoholic fatty liver disease. The studies about the pathogenesis of non-alcoholic fatty liver disease reveal that inflammatory factors could also influence its emergence and development. Here is to explain the interdependence of the two diseases on the molecular level and provide a basis for prediction of disease risk with inflammatory factors in clinical.