抗抑郁药物致性功能障碍的临床研究进展

Clinical Research Progress of Antidepressant Drugs Causing Sexual Dysfunction

抗抑郁药除了具有抗抑郁及抗焦虑的临床治疗作用外,同样具有不良反应。抗抑郁药物的不良反应一般可分为中枢性不良反应和外周性不良反应。其中抗抑郁药物对患者性功能的影响属于外周性不良反应。抗抑郁药物会引起性功能障碍已成为共识。因此,在选择抗抑郁药物时应考虑到性功能方面的不良反应,了解患者服药后性功能的变化,以制订个性化的处理方案。

Antidepressants not only has the antidepressant and anxiolytic clinical effects, but also adverse reactions. General adverse antidepressant effects can be divided into central and peripheral side effects, where the influence of antidepressants on sexual function belongs to peripheral side effects. Antidepressant drugs causing sexual dysfunction has become a consensus. Therefore, when selecting antidepressant, the adverse effect on sexual function should be taken into account,and the patient＇s sexual function change after medication should be inquired, so as to develop individualized treatment program.