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Wnt信号通路在胶质瘤中的研究进展 被引量:5

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摘要 Wnt信号通路是胚胎及器官发育的重要信号通路之一,在机体内参与调控多种细胞的增殖、分化、极化、迁移及凋亡等基因表达;Wnt信号通路的失调与肿瘤的发生发展密切相关。近年来的研究发现,胶质瘤的发病机理及耐药性等多涉及Wnt信号通路的异常激活。本文主要探讨Wnt信号通路在胶质瘤领域的最新研究进展,旨在进一步探索该通路治疗胶质瘤的可能。
作者 陈亮 李青松
出处 《国际神经病学神经外科学杂志》 北大核心 2016年第2期184-188,共5页 Journal of International Neurology and Neurosurgery
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