绝经女性早期补充小剂量激素对提高其生活质量的临床观察

Clinical Observation on Early Supplementation of Low Dose Hormone for Menopausal Women to Improve Quality of Life

目的:研究绝经早期女性小剂量激素补充治疗(HRT)对提高其生活质量的效果。方法:选取2014年8月-2015年2月于本院接受定期体检的188例绝经早期女性作为研究对象,根据是否使用1年的小剂量激素补充治疗将其分为对照组和试验组,每组94例。每3个月检查1次,比较两组女性乳腺、骨质及血脂指标变化情况。结果:1年后,试验组在乳腺疼痛肿胀、乳腺增生、骨质疏松方面均优于对照组,比较差异均有统计学意义(P<0.05);试验组1年后甘油三酯(TG)和总胆固醇(TC)均低于1年前,比较差异均有统计学意义(P<0.05)。结论:小剂量激素补充对改善绝经早期妇女乳腺、骨质疏松情况及降低心血管疾病风险作用较明显。

Objective： To study the early menopause women low doses of hormone replacement therapy （HRT） to improve the effectiveness of the quality of life.Method： From August 2014 to February 2015, 188 cases of early menopause women in our hospital who received regular medical examination were selected as the research object, they were divided into the control group and the experimental group according to whether use of 1 year of low dose hormone replacement therapy, each group had 94 eases.Every 3 months checked 1 time, the changes of breast, bone and blood lipid indexes were compared in two groups of woman.Result： One years later, the experimental group was better than the control group in breast pain and swelling, breast hyperplasia and osteoporosis, the differences were statistically significant （ P〈0.05 ） .1 year later, triglyceride （ TG ） and （ TC ） in experimental group were lower than 1 years ago, the differences were statistically significant （ P〈0.05 ） . Conclusion： Low dose hormone supplement to improve the early menopause women breast, osteoporosis and reduce the risk of cardiovascular disease effect is obvious.