吉林省手足口病重症病例发病危险因素研究

Analysis for the risk factors of severe hand foot mouth disease cases in Jilin province

目的掌握吉林省手足口病重症病例的发病危险因素,为采取针对性干预措施,降低重症病例的发生提供科学依据。方法采用1∶1匹配的病例对照研究方法,对手足口病重症病例和所选对照进行现场问卷调查,对调查结果进行相关危险因素的单因素和多因素分析。结果EV71感染是发生重症病例的危险因素,其OR值为24.46（95%CI：2.75~217.94）;而初诊正确诊断手足口病为保护因素,OR值为0.07（95% CI：0.01~0.72）。结论EV71感染可作为早期识别重症病例的参考指标,而及时、明确诊断为手足口病有助于减少手足口病重症病例的发生。

Objective To understand the risk factors of severe cases of HFMD in Jilin Province,to take targeted intervention measures and provide scientistic basis for reducing the occurrence of severe cases. Methods 1： 1 matched case-control study method was used to research about cases of HFMD and selected cases. Then according to the results,analyse of single factor and multi factors of related risk factors was carried out. Results The infection of EV71 was a risk factor for the occurrence of severe cases,the figure of OR was 24.46（ 95% CI： 2.75-217.94）,and protective factor was newly diagnosed HFMD correctly,the figure of OR was 0.07（ 95% CI： 0.01-0.72）. Conclusion Infection of EV71 can be used as a reference index for knowing severe cases earlier,diagnosing HFMD clearly in time. It is advantaged to reduce the occurrence of severe hand foot mouth disease cases.