浙江省永康市第一人民医院2014-2015年癌痛规范化病房止痛药物使用情况分析

Analysis application status of cancer pain medication in GPM -ward of Yongkang First People＇s Hospital from 2014 to 2015

目的：调查和分析永康市第一人民医院癌痛示范病房“三阶梯”止痛药物的临床应用情况，为临床合理使用癌痛治疗药物提供参考。方法通过该院医院信息管理系统（HIS 系统），统计分析该院2014年1月至2015年12月癌痛病房癌痛治疗药物的应用数据。结果该院癌痛治疗药物金额占比以第三阶梯药物为主，根据用药频度（DDDs）排序，塞来昔布＞曲马朵缓释片＞羟考酮缓释片＞吗啡缓释片＞芬太尼透皮贴剂，塞来昔布多用于辅助用药；曲马朵缓释片金额占比和 DDDs 下降，符合目前美国国家综合癌症网络（NCCN）指南弱化二阶梯药物趋势；第三阶梯主要以羟考酮缓释片为主，金额占比和 DDDs 呈增长趋势。2014年麻醉处方合格率为93．5％、癌痛治疗病历合格率为80．5％，2015年麻醉处方合格率提高至97．5％，病历合格率提高至91．5％。结论该院癌痛病房癌痛治疗药物使用情况基本规范，遵循口服给药、按阶梯用药、按时给药、个体化给药的原则。

Objective To investigate and analyze the application of three steps therapy analgesics in good pain management（GPM）-ward,in order to provide rational analgesics drug application in clinical practice.Methods Through the hospital HIS system,the application data of analgesics in GPM-ward from Jan.2014 to Dec.2015 were collected and analyzed.Results The sum and proportion of the strong opioid drug was lined first.The total DDDs of the three -stage analgesics ranked from high to low was celecoxib 〉tramadol 〉oxycontin 〉morphine 〉fentanyl trans-dermal.The celecoxib was usually assisted the other;in addition,tramadol＇s DDDs and expense amount decreased, which was in the line with NCCN guidelines.Moreover,oxycontin＇s DDDs and expense amount increased.As well as, anesthesia prescription qualified rate was 93.5%,medical record standard rate was 80.5% in 2014,prescription qual-ified rate was rose to 97.5%,medical record standard rate was rose to 91.5% in 2015.Conclusion The application of cancer pain drug was basically rational in GPM-ward,which is in line with the principles of cancer pain relief ＂by the mouth,by the clock,by the ladder and for the individual＂.