酒精中毒患者血酒精浓度医学检验探析

A study to medical test analysis of blood alcohol concentration on patients with alcoholism

〔目的〕探讨应用纳洛酮治疗急性酒精中毒的最适临床分期与血液中的最适酒精浓度(Blood alcohol concentration,BAC),给临床纳洛酮用药提供参考。〔方法〕通过收治60例急性酒精中毒患者,随机分为两组,一组使用纳洛酮治疗,另一组采取常规治疗方法,回顾分析临床恢复过程以及血液中酒精浓度的变化过程。〔结果〕BAC在0.20%(200 g/100 L)以上时运用纳洛酮效果显著,可明显降低患者清醒时间,减少患者心悸、胸闷症状。〔结论〕建议临床使用纳洛酮治疗急性酒精中毒的最适临床阶段是共济失调伴心悸与呼吸困难以及昏睡程度以上,BAC≥0.20%(200 g/100 L)时,这样能最大程度的减少患者的昏迷时间,减轻酒精中毒症状,减缓病人痛苦,并且可以防止临床上的药物滥用或未及时应用。

〔Objective〕To explore the application of naloxone in treatment of acute alcohol intoxication of optimal clinical stage and the optimal alcohol concentration in the blood.Make Suggestions and guidance for clinical naloxone administration.〔Methods〕By treating 100 cases of patients with acute alcoholism who are randomly divided into two groups,one uses naloxone while the other uses conventional treatment methods. And then observe their clinical recovery process and the changing process of alcohol concentration in blood.〔Results〕The effect of using naloxone is the most obvious when the alcohol concentration in the blood is above 0.20%（ 200 g / 100 L）. It can obviously reduce the patients＇ awake time and reduce patients＇ symptoms of heart palpitations and chest distress.〔Conclusion〕To recommend the clinical use of naloxone in treatment of acute alcohol intoxication is the optimal clinical stage of ataxia with respiratory depression or more serious and BAC≥0.20%（ 200 g / 100 L）. It can reduce the patiences＇ time in a coma and reduce alcohol poisoning symptoms. What＇s more, it can ease the patients＇ pain and prevent the clinical drug abuse.