期刊文献+

虫草素抑制血管平滑肌细胞增殖的可能机制

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摘要 虫草素是第一个从真菌中分离出来的核苷类抗菌素,具有免疫刺激、抑菌、抗肿瘤、抗炎等非常广谱的生物活性及药理作用,目前已经成为一个研究热点。同时,国内外的多项研究都已证实虫草素能明显抑制血管平滑肌细胞的增殖,并从多个方面对其相关机制进行了探讨。现就虫草素抑制血管平滑肌细胞增殖的可能机制作一综述。
出处 《牡丹江医学院学报》 2016年第4期110-112,122,共4页 Journal of Mudanjiang Medical University
基金 国家自然科学基金(No.81403044) 广东省自然科学基金(S2013010015120)
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  • 1R O S S R . T h e pathogenesis of atherosclerosis : a perspective for the1 9 9 0 s [J] . N a t u r e , 1 9 9 3 , 3 6 2 ( 1 0 ) :8 0 1 - 8 0 9 .
  • 2C H A N G W , L I M S , S 0 N G H , e t al. C ordycepin inhibits vasculars m o o t h m u s c l e cell proliferation [J]. E u r o p e a n journal of p h a r m a cology,2 0 0 8 , 5 9 7 ( 1 - 3 ) :6 4 - 6 9 .
  • 3D W I V E D I A , S L A T E R S C , G E O R G E S J. M M P - 9 a n d - 12cause N - cadherin shedding a n d thereby beta - catenin signallinga n d vascular s m o o t h m u s c l e cell proliferation [J]. Cardiovascularresearch. 2 0 0 9 , 8 1 ( 1) : 1 7 8 - 186.
  • 4李一平,唐梅,伏静媛,王银娣.球囊扩张术对血管平滑肌细胞COX-2表达的影响及其增殖凋亡分子机制研究[J].中国分子心脏病学杂志,2006,6(6):338-341. 被引量:2
  • 5E G U C H I S , I W A S A K I H , U E N 0 H , e t al. Intracellular Signaling ofAngiotensin II - in d u c e d p 7 0 S 6 Kin a s e Phosphorylation at S e r 4 11in Vascular S m o o t h M u s c l e Cells possible requirement of epidermalgrowth factor receptor, ras, extracellular signal - regulated kina s e ,a n d akt [J]. Journal of Biological Chemistry, 1 9 9 9 , 2 7 4 ( 5 2 ) :3 6 8 4 3 - 3 6 8 5 1 .
  • 6D E N H A R D T D T. Signal - transducing protein phosphorylationcascades medi a t e d b y R a s / R h o proteins in the mammalian cell:the potential for multiplex signalling [J]. T h e Biochemical journal, 1 9 9 6 , 3 1 8 ( Pt 3 ) :7 2 9 - 747.
  • 7J u n g S M , P a r k S S , K i m W J,et al. R a s / E R K l p a t h w a y regulationof p 2 7 K I P l - media t e d G 1 - p h a s e cell - cycle arrest in cordycepin- in d u c e d inhibition of the proliferation of vascular s m o o t h musc l ecells[J] . E u r o p e a n journal of p h a r m a c o l o g y , 2 0 1 2 , 6 8 1 ( 1) : 15 -22.
  • 8G A O B A , Y A N G J, H U A N G J,et al. Co r d y c e p s sinensis extractsuppresses hypoxia - i n d u c e d proliferation of rat p u l m o n a r y arterys m o o t h m u s c l e cells[J]. Saudi medical journal,2 0 1 0 , 3 1 ( 9 ) :9 7 4- 9 7 9 .
  • 9W A N G L , F U S T E R M , S R I R A M A R A O P , e t al. Endothelial h e p a ransulfate deficiency impairs L - selectin - a n d c h e m o k i n e - m e diatedneutrophil trafficking during inflammatory responses [J].Nature i m m u n o l o g y , 2 0 0 5 , 6 ( 9 ) :9 0 2 - 9 1 0 .
  • 10Z H A N G Y , O U Y A J G P , L A I W , e t al. C ordycepin inhibits expressionof s y n d e c a n - 4 protein in rat vascular s m o o t h mus c l ecells i n d u c e d b y t u m o r necrosis factor - a in vitro [J]. Journal ofG u a n g d o n g Pharmaceutical College,2 0 0 9 , 2 5 ( 6 ) :6 0 6 - 6 1 1 .

二级参考文献10

  • 1[1]Indolfi C,Mongiardo A,Curcio A,et al.Molecular mechanisms of in-stent restenosis and approach to therapy with eluting stents.Trends Cardiovasc Med,2003,13 (4):142-148.
  • 2[2]Francis DJ,Parish CR,McGarry M,et al.Blockade of vascular smooth muscle cell proliferation and intimal thickening after balloon injury by the sulfated oligosaccharide PI-88:phosphomannopentaose sulfate directly binds FGF-2,blocks cellular signaling,and inhibits proliferation.Circ Res,2003,92(8):e70-e77.
  • 3[3]Song X,Lin HP,Johnson AJ,et al.Cyclooxygenase-2,player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells.J Natl Cancer Inst,2002,94:585-591.
  • 4[4]Brennan M M,Lambkin H A,Sheehan C D,et al.Detection of high risk subtypes of human papillomavirus in cervix swabs:routine use of the Digene Hybrid Capture assay and polymerase chain reaction analysis.Br J Biomed Sci,2001,58:24-29.
  • 5[6]Takahiro N,Yasuhiro S,Tetsuo N,et al.Titanium-alloy particles induced cyclooxygenase-2 in human macrophage-like cells in vitro.Kobe J.Med.Sci,2002,48:115-123.
  • 6[7]Pai R,Nakamura T,Moon WS,et al.Prostaglandins promote colon cancer cell invasion; signaling by cross-talk between two distinct growth factor receptors.ASEB J,2003,17(12):1640-1647.
  • 7[8]Ming Li,Xiuyuan,Xiao-Chun.Xu Inhibition of apoptosis in colon cancer cells by cyclooxygenase-2 inhibitor NS-398 through a cytochrome c-dependent pathway.Clin.Cancer Res,2001,7:1010-1016.
  • 8[9]Marks AR.Rapamycin:signaling in vascular smooth muscle.Transplant Proc,2003,35(3 Suppl):231S-233S.
  • 9[10]Darnell JE.STATs and gene regulation.Science,1997,277:1630-1633.
  • 10[11]Englesbe MJ,Deou J,Bourns BD,et al.Interleukin-1beta inhibits PDGF-BB-induced migration by cooperating with PDGF-BB to induce cyclooxygenase-2 expression in baboon aortic smooth muscle cells.J Vasc Surg,2004,39 (5):1091-1096.

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