新生儿严重快速心律失常应用胺碘酮治疗的临床分析

Clinical Analysis of Amiodarone in the Treatment of Severe Neonatal Arrhythmia

目的：分析新生儿严重快速心律失常应用胺碘酮治疗的临床效果。方法：试验对象来自某院2013年6月～2015年8月19例新生儿严重快速心律失常患儿,分组后,对照组10例患儿施行对症处理,治疗组9例患儿增加胺碘酮治疗,对两组治疗效果、心电图效果、心肌标志物进行对比。结果：治疗组患儿总有效率、心电图效果均明显高于对照组,差异有统计学意义（P〈0.05）;干预后心肌标志物肌红蛋白、肌钙蛋白、肌酸激酶同工酶均显著降低,但治疗组降低幅度优于对照组,差异有统计学意义（P〈0.05）。结论：新生儿严重快速心律失常应用胺碘酮治疗的临床效果确切,可有效改善患儿预后,值得推广。

Objective：To analyze the clinical effect of amiodarone in the treatment of severe neonatal ar-rhythmia.Methods：19 cases of neonatal severe arrhythmia treated in a hospital from June 2013 to August 2015 were taken as research object,who were divided into the control group with 10 cases treated with ex-pectant treatment and 9 cases in the treatment group treated with amiodarone on the basis of expectant treat-ment.Then compare the curative effect,electrocardiogram and cardiac markers of the two groups.Results：The total efficiency and effect of electrocardiogram （ECG）of the treatment group were significantly higher than those in the control group,and the difference is statistically significant （P〈0.05）;after intervention, myocardial markers matter of myoglobin and troponin and creatine kinase isoenzyme were significantly de-creased,but the treatment group reduced more than the control group,and the difference is statistically sig-nificant （P〈0.05）.Conclusion：The clinical effect of amiodarone in the treatment of severe neonatal arrhyth-mia is effective,which can effectively improve the prognosis of patients,and is worthy to be popularized.