负性情绪对原发性肝癌患者姑息治疗中生活质量的影响

Effects of negative emotion on quality of life in patients with primary liver cancer

目的:探讨负性情绪对原发性肝癌患者姑息治疗中生活质量的影响。方法:选取原发性肝癌患者100例作为观察组,同期健康查体者100例作为对照组。分别记录两组研究对象的焦虑自评量表(SAS)、抑郁自评量表(SDS)以及生活质量核心问卷量表的分值,比较两组研究对象负性情绪与生活质量的相关性。结果:对照组研究对象的SDS、SAS评分分别为(28.03±9.44)分和(30.89±7.49)分,而观察组患者分别为(39.45±8.72)分和(38.42±7.56)分,两组研究对象比较差异有统计学意义(P<0.05);观察组患者的整体质量评分为(61.54±12.34)分,处于较差的水平;负性情绪与整体质量、功能总分呈现负相关的关系(r=-0.29^-0.66,P<0.05),而与症状评分呈现正相关的关系(r=0.33~0.60,P<0.05)。结论:负性情绪可严重降低原发性肝癌患者姑息治疗中生活质量。

Objective： To analyze effects of negative emotion on quality of life in patients with primary liver cancer. Methods：100 patients with primary lung cancer were selected as the observation group,and 100 healthy persons were used as control group. The scores of self-rating anxiety scale（ SAS）,self-rating depression Scale（ SDS） and quality of life core questionnaire were used to analyze the relationship between negative emotion and quality of life. Results： The scores of SDS and SAS in the control group were（ 28.03±9.44） and（ 30.89±7.49） points,while those of observation group were（ 39.45±8.72） and（ 38.42±7.5）,and the differences were statistically significant（ P〈0.05）. The total score of observation group was 61.54±12.34 and was poor. The negative emotion of observation group was negatively correlated with the overall quality and total functional score（ r =-0.29-0.66,P〈0.05）,but positively correlated the symptom score（ r = 0.33- 0.60,P〈0.05）. Conclusions： Negative emotions seriously reduce the quality of life in the patients with primary liver cancer.