胰腺实性假乳头状瘤的诊断与治疗

Diagnosis and treatment of solid pseudopapillary neoplasms of the pancreas

胰腺实性假乳头状瘤（SPN）是一类少见的良性或低度恶性胰腺肿瘤，好发于年轻女性，一般无特异临床表现。CT及MRI检查有助于SPN的术前诊断。手术是其主要的治疗方法，放化疗效果则有待更多研究验证。肿瘤最大径〉5cm，肿瘤侵犯胰周神经、血管及脂肪组织的患者复发风险增加，但手术切除后仍能获得较好预后。

Solid pseudopapillary neoplasm of the pancreas （SPN） is a rare neoplasm which primarily affects young women without specific clinical manifestation. Computed tomography and magnetic resonance imaging contribute to the preoperative diagnosis of SPN. Surgery is the main treatment approach for SPN and more research of radiation and chemotherapy is needed. Tumor diameter larger than 5 cm, tumor infiltrating nerve, vessel or adipose tissue can increase the risk of recurrence. However, these patients can still get good prognosis after surgical resection.