加味四物汤治疗透析伴顽固性皮肤瘙痒患者48例疗效观察

Clinical effect of Jiawei Siwu decoction in treatment of dialysis patients with refractory pruritus: a clinical analysis of 48 cases

目的:观察加味四物汤治疗透析伴顽固性皮肤瘙痒(血虚风燥型)患者的临床疗效。方法:将96例透析伴顽固性皮肤瘙痒患者随机分为两组各48例,对照组给予基础治疗加血液灌流,治疗组给予基础治疗加加味四物汤治疗,两组疗程均为2个月。结果:总有效率治疗组为83.3%,对照组为60.4%,组间比较,差异有统计学意义(P<0.01);两组皮肤瘙痒程度评分治疗前后组内比较及治疗后组间比较,差异均有统计学意义(P<0.05)。结论:加味四物汤可有效改善透析患者顽固性皮肤瘙痒(血虚风燥型)症状。

Objective： To investigate the clinical effect of Jiawei Siwu decoction in the treatment of dialysis patients with refractory pruritus（ blood- deficiency and wind- dryness type）. Methods： A total of 96 dialysis patients with refractory pruritus were randomly divided into two groups,with 48 patients in each group. The patients in the control group were given basic treatment and hemoperfusion,and those in the treatment group were given basic treatment and Jiawei Siwu decoction. All the patients were treated for 2 months. Results： The overall response rate showed a significant difference between the treatment group and the control group（ 83. 3% vs60. 4%,P〈0. 01）.The pruritus score changed significantly after treatment and showed a significant differe（ P〈0. 05）. Conclusion： Jiawei Siwu decoction can effectively improve the symptoms of dialysis patients with refractory pruritus（ blood- deficiency and wind- dryness type）.