经尿道电切术同期治疗膀胱尿路上皮细胞癌合并前列腺增生患者的临床疗效

Clinical Efficacy of Transurethral Resection of Bladder and Urinary Tract Epithelial Cell Carcinoma Patients with Benign Prostatic Hyperplasia

目的探讨经尿道电切术同期治疗膀胱尿路上皮细胞癌合并前列腺增生患者的临床疗效。方法选取2012年8月至2014年8月广州市中西医结合医院收治的57例膀胱尿路上皮细胞癌合并前列腺增生患者作为研究对象,按随机数字表法将其分为A组(27例)和B组(30例)。A组患者单纯行经尿道膀胱肿瘤电切术(TURBT),B组患者在A组基础上再行TURP,比较两组患者的肿瘤复发、膀胱颈部种植转移情况及B组患者手术前后残余尿量(RUV)、最大尿流率(Qmax)、生活质量指数(QOL)、国际前列腺症状评分(IPSS)。结果术后,B组患者RUV、QOL及IPSS均明显低于手术前,Qmax明显高于手术前,差异均有统计学意义(均P<0.05)。结论同期行TURBT和TURP对膀胱尿路上皮细胞癌合并前列腺增生患者进行治疗,疗效显著,安全性高,不会增加肿瘤复发及种植转移风险,且可有效解除尿路梗阻。

Objective To investigate the clinical efficacy of transurethral surgery over the same period in patients with bladder urothelial carcinoma with benign prostatic hyperplasia.Methods Select August 2012 to 2014 August in Guangzhou traditional Chinese medicine and Western medicine combined with hospital of 57 cases of bladder urothelial cell carcinoma with benign prostatic hyperplasia patients as the research object,according to the random number table method divided into group A（27 cases） and group B（30 cases）.Patients in group A were treated by transurethral bladder tumor resection（TURBT）,group B patients in group a underwent TURP,compared two groups of patients with tumor recurrence,the bladder neck planting and group B patients before and after the residual urine volume（RUV）,maximal urinary flow rate（Qmax）,life quality index（QOL）,International Prostate Symptom Score（IPSS） transfer.Results After surgery,patients in the B group RUV,QOL and IPSS were significantly lower than that before surgery,Qmax was significantly higher than that before surgery,the differences were statistically significant（P0.05）. Conclusion Over the same period underwent TURBT and TURP for urinary bladder epithelial cell carcinoma with benign prostatic hyperplasia patients for treatment,remarkable curative effect,high safety,does not increase the recurrence and planting risk transfer and relieve the obstruction of urinary tract.