前列舒乐胶囊联合龙金通淋胶囊治疗慢性前列腺炎的疗效观察

Clinical observation of Qianlie Shule Capsules combined with Longjin Tongling Capsules in treatment of chronic prostatitis

目的探讨前列舒乐胶囊联合龙金通淋胶囊治疗慢性前列腺炎的临床疗效。方法选取2014年12月—2015年12月首都医科大学附属北京潞河医院收治的慢性前列腺炎患者86例,随机分为对照组和治疗组,每组各43例。对照组患者口服龙金通淋胶囊,2粒/次,3次/d。治疗组在对照组治疗基础上口服前列舒乐胶囊,4粒/次,3次/d。两组患者均连续治疗4周。观察两组的临床疗效,同时比较治疗前后两组慢性前列腺炎症状指数(NIH-CPSI)评分、前列腺液中的白细胞计数的变化情况。结果治疗后,对照组和治疗组的总有效率分别为79.1%、95.3%,两组总有效率比较差异有统计学意义(P<0.05)。治疗后,两组患者生活质量影响评分、排尿症状评分、疼痛评分、总评分、前列腺液白细胞数均显著降低,同组治疗前后差异均具有统计学意义(P<0.05);且治疗组的降低程度优于对照组,两组比较差异有统计学意义(P<0.05)。结论前列舒乐胶囊联合龙金通淋胶囊治疗慢性前列腺炎具有较好的临床疗效,可改善患者的临床症状,降低患者的炎症反应,具有一定的临床推广应用价值。

Objective To explore the clinical observation of Qianlie Shule Capsules combined with Longjin Tongling Capsules in treatment of chronic prostatitis. Methods Patients（83 cases） with chronic prostatitis in Beijing Luhe Hospitial Capital Medical University from December 2014 to December 2015 were randomly divided into control and treatment groups. Each group had 43 cases. The patients in the control group were po administered with Longjin Tongling Capsules, 2 grains/time, three times daily. The patients in the treatment group were po administered with Qianlie Shule Capsules on the basis of the control group, 4 grains/time, three times daily. The patients in two groups were treated for 4 weeks. After treatment, the clinical efficacies were evaluated, and the changes of NIH-CPSI scores and white blood cell count of prostatic fluid in two groups before and after treatment were compared. Results After treatment, the total efficacies in the control and treatment groups were 79.1% and 95.3%, respectively, and there were differences between two groups（P〈 0.05）. After treatment, life quality impact score, micturition symptom scores, pain score, total score, and white blood cell count of prostatic fluid in two groups were significantly decreased, and the difference was statistically significant in the same group（P〈 0.05）. After treatment, the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups（P〈 0.05）. Conclusion Qianlie Shule Capsules combined with Longjin Tongling Capsules has clinical curative effect in treatment of chronic prostatitis, and can improve the clinical symptoms, reduce inflammatory response, which has a certain clinical application value.